Ph.D. Peking University
Advisor: Zhi-Xiang Yu

Yi was born in Zhejiang, China. He received his B.S. degrees in Chemistry and Economics from Peking University. Then, he pursued graduate studies under the supervision of Professor Zhi-Xiang Yu at Peking University. His doctoral research was mainly focused on mechanistic studies on catalytic reactions and carbon-to-carbon proton transfers. He has also been trained in organic synthesis. After he got his Ph.D. degree, he continued his research in the same group. In September 2021, he joined the Lin group at Cornell University as a postdoctoral associate.

Publications:

28. Liu, J.; Rong, J.; Wood, D. P.; Wang, Y.; Liang, S. H.; Lin, S. Co-Catalyzed Hydrofluorination of Alkenes: Photocatalytic Method Development and Electroanalytical Mechanistic Investigation. J. Am. Chem. Soc. 2024, 146, 4380.
27. Wang, Y.; Deng, J.; Ressler, A. J.; Lin, S. Electroreductive Radical Addition−Polar Cyclization Cascade to Access Cycloalkanes. Org. Lett. 2024, 26, 116.
26. Zhang, W.; Guan, W.; Wang, Y.; Lin, S.; See, K. A. Enabling Al Sacrificial Anodes in Tetrahydrofuran Electrolytes for Reductive Electrosynthesis. Chem. Sci. 2023, 14, 13108.
25. Lu, L.; Wang, Y.; Zhang, W.; Zhang, W.; See, K. A.; Lin, S. Three-Component Cross-Electrophile Coupling: Regioselective Electrochemical Dialkylation of Alkenes. J. Am. Chem. Soc. 2023, 145, 22298.
24. Zhang, W.; Gu, C.; Wang, Y.; Ware, S. D.; Lu, L.; Lin, S.; Qi, Y.; See, K. A. Improving the Mg Sacrificial Anode in Tetrahydrofuran for Synthetic Electrochemistry by Tailoring Electrolyte Composition. JACS Au 2023, 3, 2280.
23. Lu, Z.; Ju, M.; Wang, Y.; Meinhardt, J. M.; Martinez Alvarado, J. I.; Villemure, E.; Terrett, J. A.; Lin, S. Regioselective Aliphatic C–H Functionalization Using Frustrated Radical Pairs. Nature 2023, 619, 514.
22. Guan, W.; Lu, L.; Jiang, Q.; Gittens, A. F.; Wang, Y.; Novaes, L. F. T.; Klausen, R. S.; Lin, S. An Electrochemical Strategy to Synthesize Disilanes and Oligosilanes from Chlorosilanes. Angew. Chem., Int. Ed. 2023, 62, e202303592.
21. Sun, G.-Q.; Yu, P.; Zhang, W.; Zhang, W.; Wang, Y.; Liao, L.-L.; Zhang, Z.; Li, L.; Lu, Z.; Yu, D.-G.; Lin, S. Electrochemical Reactor Dictates Site Selectivity in N-Heteroarene Carboxylations. Nature 2023, 615, 67.
20. Novaes, L. F. T.; Wang, Y.; Liu, J.; Riart-Ferrer, X.; Lee, W.-C. C.; Fu, N.; Ho, J. S. K.; Zhang, X. P.; Lin, S. Electrochemical Diazidation of Alkenes Catalyzed by Manganese Porphyrin Complexes with Second-Sphere Hydrogen-Bond Donors. ACS Catal. 2022, 12, 14106.
19. Zhang, W.; Lu, L.; Zhang, W.; Wang, Y.; Ware, S. D.; Mondragon, J.; Rein, J.; Strotman, N.; Lehnherr, D.; See, K. A.; Lin, S. Electrochemically Driven Cross-Electrophile Coupling of Alkyl Halides. Nature 2022, 604, 292.
18. Wang, Y.; Liao, W.; Wang, Y.; Jiao, L.; Yu, Z.-X. Mechanism and Stereochemistry of Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene−Vinylcyclopropanes and Carbon Monoxide Revealed by Visual Kinetic Analysis and Quantum Chemical Calculations. J. Am. Chem. Soc. 2022, 144, 2624.
17. Yao, W.-W.; Li, R.; Chen, H.; Chen, M.-K.; Luan, Y.-X.; Wang, Y.; Yu, Z.-X.; Ye, M. Ni-Catalyzed Hydroaminoalkylation of Alkynes with Amines. Nat. Comm. 2021, 12, 3800.
16. Zhang, L.; An, K.; Wang, Y.; Wu, Y.-D.; Zhang, X.; Yu, Z.-X.; He, W. A Combined Computational and Experimental Study of Rh-Catalyzed C−H Silylation with Silacyclobutanes: Insights Leading to a More Efficient Catalyst System. J. Am. Chem. Soc. 2021, 143, 3571.
15. Fan, X.; Zhang, P.; Wang, Y.; Yu, Z.-X. Mechanism and Regioselectivity of Intramolecular [2+2] Cycloaddition of Ene−Ketenes: A DFT Study. Eur. J. Org. Chem. 2020, 2020, 5985.
14. Wang, Y.; Cai, P.-J.; Yu, Z.-X. Mechanistic Study on Gold-Catalyzed Cycloisomerization of Dienediynes Involving Aliphatic C−H Functionalization and Inspiration for Developing a New Strategy to Access Polycarbocycles. J. Am. Chem. Soc. 2020, 142, 2777.
13. Wang, Y.; Yu, Z.-X. Symmetric C···H···C Hydrogen Bonds Predicted by Quantum Chemical Calculations. J. Org. Chem. 2020, 85, 397.
12. Zhang, C.; Wang, Y.; Song, Y.; Gao, H.; Sun, Y.; Sun, X.; Yang, Y.; He, M.; Yang, Z.; Zhan, L.; Yu, Z.-X.; Rao, Y. Synthesis of Quaternary Carbon-Centered Benzoindolizidinones via Novel Photoredox-Catalyzed Alkene Aminoarylation: Facile Access to Tylophorine and Analogues. CCS Chem. 2019, 1, 352.
11. She, Z.; Wang, Y.; Wang, D.; Zhao, Y.; Wang, T.; Zheng, X.; Yu, Z.-X.; Gao, G.; You, J. Two-Fold C−H/C−H Cross-Coupling Using RhCl₃·3H₂O as the Catalyst: Direct Fusion of N-(Hetero)arylimidazolium Salts and (Hetero)arenes. J. Am. Chem. Soc. 2018, 140, 12566.
10. Marichev, K. O.; Wang, Y.; Carranco, A. M.; Garcia, E. C.; Yu, Z.-X.; Doyle, M. P. Rhodium(II)-Catalysed Generation of Cycloprop-1-en-1-yl Ketones and Their Rearrangement to 5-Aryl-2-siloxyfurans. Chem. Commun. 2018, 54, 9513.
9. Li, S.-J.; Wang, Y.; Xu, J.-K.; Xie, D.; Tian, S.-K.; Yu, Z.-X. Formal Insertion of Imines (or Nitrogen Heteroarenes) and Arynes into the C−Cl Bond of Carbon Tetrachloride. Org. Lett. 2018, 20, 4545.
8. Wang, Y.; Yu, Z.-X. Intra- versus Intermolecular Carbon-to-Carbon Proton Transfers in the Reactions of Arynes with Nitrogen Nucleophiles: A DFT Study. J. Org. Chem. 2018, 83, 5384.
7. Wang, Y.; Yu, Z.-X. Sigmatropic Proton Shifts: A Quantum Chemical Study. Org. Biomol. Chem. 2017, 15, 7439.
6. Wang, Y.; Cai, P.-J.; Yu, Z.-X. Carbanion Translocations via Intramolecular Proton Transfers: A Quantum Chemical Study. J. Org. Chem. 2017, 82, 4604.
5. Zhang, L.; Wang, Y.; Yao, Z.-J.; Wang, S.; Yu, Z.-X. Kinetic or Dynamic Control on a Bifurcating Potential Energy Surface? An Experimental and DFT Study of Gold-Catalyzed Ring Expansion and Spirocyclization of 2-Propargyl-β-tetrahydrocarbolines. J. Am. Chem. Soc. 2015, 137, 13290.
4. Wang, Y.; Yu, Z.-X. Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene−Vinylcyclopropanes and CO: Reaction Design, Development, Application in Natural Product Synthesis, and Inspiration for Developing New Reactions for Synthesis of Eight-Membered Carbocycles. Acc. Chem. Res. 2015, 48, 2288.
3. Cai, P.-J.; Wang, Y.; Liu, C.-H.; Yu, Z.-X. Gold(I)-Catalyzed Polycyclization of Linear Dienediynes to Seven-Membered Ring-Containing Polycycles via Tandem Cyclopropanation/Cope Rearrangement/C−H Activation. Org. Lett. 2014, 16, 5898.
2. Dong, Z.; Liu, C.-H.; Wang, Y.; Lin, M.; Yu, Z.-X. Gold(I)-Catalyzed endo-Selective Intramolecular α‐Alkenylation of β‐Yne−Furans: Synthesis of Seven‐Membered‐Ring‐Fused Furans and DFT Calculations. Angew. Chem., Int. Ed. 2013, 52, 14157.
1. Yeom, H.-S.; Koo, J.; Park, H.-S.; Wang, Y.; Liang, Y.; Yu, Z.-X.; Shin, S. Gold-Catalyzed Intermolecular Reactions of Propiolic Acids with Alkenes: [4 + 2] Annulation and Enyne Cross Metathesis. J. Am. Chem. Soc. 2012, 134, 208.

Contact:
Yi Wang